Litcius/Paper detail

Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response

Laura Poillet-Perez, Daniel W. Sharp, Yang Yang, Saurabh V. Laddha, Maria Ibrahim, Praveen K. Bommareddy, Zhixian Hu, Joshua A Vieth, Michael Haas, Marcus Bosenberg, Joshua D. Rabinowitz, Jian Cao, Jun‐Lin Guan, Shridar Ganesan, Chang S. Chan, Janice M. Mehnert, Edmund C. Lattime, Eileen White

2020Nature Cancer111 citationsDOIOpen Access PDF

Topics & Concepts

AutophagyImmune systemBiologyCell biologyCancer researchTumor microenvironmentImmune toleranceT cellCellIntracellularProgrammed cell deathImmunologyApoptosisBiochemistryAutophagy in Disease and TherapyEpigenetics and DNA MethylationMicroRNA in disease regulation