Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives
Montaser Sh. A. Shaykoon, Adel A. Marzouk, Osama M. Soltan, Amira S. Wanas, Mohamed M. Radwan, Ahmed M. Gouda, Bahaa G. M. Youssif, Mohamed Abdel‐Aziz
Topics & Concepts
ChemistryDocking (animal)Trypanosoma bruceiStereochemistryOxadiazoleIC50CytotoxicityActive siteEnzymeTriazoleProton NMR1,2,4-TriazoleIn vitroStructure–activity relationshipBiochemistryOrganic chemistryMedicineNursingGeneResearch on Leishmaniasis StudiesSynthesis and biological activityQuinazolinone synthesis and applications