Near-infrared fluorescent probe for hydrogen sulfide: high-fidelity ferroptosis evaluation <i>in vivo</i> during stroke
Tianyu Liang, Taotao Qiang, Longfang Ren, Fei Cheng, Baoshuai Wang, Mingli Li, Wei Hu, Tony D. James
Abstract
A H 2 S triggered and H 2 S releasing near-infrared fluorescent probe (HL-H2S) was developed. HL-H2S does not interfere with the progression of ferroptosis by consuming H 2 S, thus enabling high-fidelity in situ imaging of ferroptosis.
Topics & Concepts
Hydrogen sulfideIn vivoFluorescenceChemistryInfraredStroke (engine)HydrogenPhotochemistryBiophysicsBiologyPhysicsSulfurOpticsEngineeringGeneticsOrganic chemistryAerospace engineeringSulfur Compounds in BiologyObstructive Sleep Apnea ResearchMolecular Sensors and Ion Detection