Discovery of BW710 as a potent, selective and orally bioavailable fibroblast growth factor receptor 2 (FGFR2) inhibitor
Bowen Yang, Qiuju Xun, Yuan Tian, Huiqiong Li, Pinglian Wu, Yang Zhou, Shaohua Chang, Zhen Wang, Ke Ding, Dawei Ma
Topics & Concepts
ChemistryBioavailabilityFibroblast growth factor receptor 1Fibroblast growth factorFibroblast growth factor receptor 2Fibroblast growth factor receptorOrally activePharmacologyFibroblast growth factor receptor 3ReceptorGrowth factor receptorBiochemistryIn vitroMedicineFibroblast Growth Factor ResearchKruppel-like factors researchEpigenetics and DNA Methylation