Esculentoside H reduces the PANoptosis and protects the blood-brain barrier after cerebral ischemia/reperfusion through the TLE1/PI3K/AKT signaling pathway
Kuo Zhang, Zhichao Wang, Hongxue Sun, Huimin Long, Ying-Ju Wang
Topics & Concepts
MMP9Blood–brain barrierPI3K/AKT/mTOR pathwayMatrix metalloproteinaseIschemiaProtein kinase BReperfusion injuryChemistrySignal transductionMedicinePharmacologyCell biologyNeuroscienceCentral nervous systemBiologyDownregulation and upregulationBiochemistryInternal medicineGeneBarrier Structure and Function StudiesNeuroinflammation and Neurodegeneration MechanismsFlavonoids in Medical Research