Comparing tocilizumab biosimilar BAT1806/BIIB800 with reference tocilizumab in patients with moderate-to-severe rheumatoid arthritis with an inadequate response to methotrexate: a phase 3, randomised, multicentre, double-blind, active-controlled clinical trial
Xiaomei Leng, Piotr Leszczyński, Sławomir Jeka, Shengyun Liu, Huaxiang Liu, Małgorzata Miakisz, Jieruo Gu, L. Kilasonia, Mykola Stanislavchuk, Xiaolei Yang, Yinbo Zhou, Qingfeng Dong, Mourad F. Rezk, Marian Mitroiu, Janet Addison, Xiaofeng Zeng
Topics & Concepts
TocilizumabMedicineRheumatoid arthritisBiosimilarClinical endpointInternal medicineMethotrexateAdverse effectRheumatologyRandomized controlled trialBiosimilars and Bioanalytical MethodsRheumatoid Arthritis Research and TherapiesPharmacogenetics and Drug Metabolism