PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1
Lingling Zhang, Yaqian Qin, Guang Wu, Jieyi Wang, Jiawei Cao, Yaqi Wang, Du Wu, Kaiyan Yang, Zhiguang Zhao, Licai He, Jianxin Lyu, Hongzhi Li, Haihua Gu
Topics & Concepts
Cancer researchBreast cancerMetastasisBiologyUbiquitin ligaseCarcinogenesisDownregulation and upregulationCancerGene knockdownImmunohistochemistryMetastatic breast cancerProto-oncogene tyrosine-protein kinase SrcUbiquitinKinaseImmunologyCell cultureCell biologyGeneGeneticsBiochemistryUbiquitin and proteasome pathwaysCancer-related gene regulationGlycosylation and Glycoproteins Research