Selective FRET nano probe based on carbon dots and naphthalimide–isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury
Yueci Wu, Lu-Lu Sun, Hai‐Hao Han, Xiao‐Peng He, Weiguo Cao, Tony D. James
Abstract
Ratiometric FRET-based probe CD–N-I was developed to detect exogenous ONOO − in live cells and endogenous ONOO − in APAP-induced liver injury of HepG2 cells.
Topics & Concepts
PeroxynitriteIsatinChemistryFörster resonance energy transferEndogenyDrugLiver injuryBiophysicsNanotechnologyFluorescencePharmacologyBiochemistryMedicineMaterials scienceOrganic chemistryBiologySuperoxideQuantum mechanicsPhysicsEnzymeCarbon and Quantum Dots ApplicationsMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniques