Fostamatinib alleviates temporomandibular joint osteoarthritis by maintaining cartilage homeostasis through MAPK/NF-κB and AKT/mTOR pathways
Yuxin Zhang, Dahe Zhang, Qingyu Xu, Simo Xia, Pei Shen, Chi Yang
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BNF-κBOsteoarthritisMAPK/ERK pathwayMedicineSignal transductionPhosphorylationHomeostasisCancer researchInternal medicineCell biologyBiologyPathologyAlternative medicineOsteoarthritis Treatment and MechanismsMedicinal plant effects and applicationsInflammatory mediators and NSAID effects