The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway
Lijun Qiao, Qiangnu Zhang, Zhe Sun, Quan Liu, Zongze Wu, Weibin Hu, Shiyun Bao, Qinhe Yang, Liping Liu
Topics & Concepts
AutophagyDeubiquitinating enzymeCancer researchBiologyUbiquitinCell growthPI3K/AKT/mTOR pathwayMetastasisE2F1MAPK/ERK pathwayCell biologyApoptosisSignal transductionCancerCell cycleBiochemistryGeneGeneticsUbiquitin and proteasome pathwaysAutophagy in Disease and TherapyCancer-related Molecular Pathways