Electrochemical Isothiocyanation of Primary Amines
Cyrille Kiaku, Jamie M. Walsh, Matthew C. Leech, Darren L. Poole, J. S. Mason, Iain C. A. Goodall, Perry Devo, Kevin Lam
Abstract
Isothiocyanates are ubiquitous building blocks used across the fields. Nevertheless, their classical syntheses very often rely on the use of toxic and expensive reagents. Herein, we report a new practical, mild, high-yielding, and supporting-electrolyte-free electrochemical method for the preparation of aliphatic and aromatic isothiocyanates from amine and carbon disulfide.
Topics & Concepts
ChemistryElectrochemistryPrimary (astronomy)Amine gas treatingReagentCombinatorial chemistryCarbon disulfideElectrolyteSupporting electrolyteDisulfide bondOrganic chemistryNanotechnologyElectrodeBiochemistryPhysical chemistryPhysicsAstronomyMaterials scienceSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsGenomics, phytochemicals, and oxidative stress