Litcius/Paper detail

POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status

Karl P. Hodel, Meijuan J.S. Sun, Nathan Ungerleider, Vivian S. Park, Leonard G. Williams, David L. Bauer, Victoria E. Immethun, Jieqiong Wang, Zucai Suo, Hua Lu, James B. McLachlan, Zachary F. Pursell

2020Molecular Cell74 citationsDOIOpen Access PDF

Topics & Concepts

BiologyGeneticsMutationDNA mismatch repairMutagenesisMutantExonucleasePopulationMutation rateAlleleGeneDNA repairMolecular biologyDNA polymeraseSociologyDemographyCancer Genomics and DiagnosticsDNA Repair MechanismsGenetic factors in colorectal cancer