Cathepsin B aggravates acute pancreatitis by activating the NLRP3 inflammasome and promoting the caspase-1-induced pyroptosis
Jianhua Wang, Lichun Wang, Xiao-Fei Zhang, Yanfen Xu, Lei Chen, Weiyu Zhang, Enhe Liu, Chaoxing Xiao, Qiuye Kou
Topics & Concepts
PyroptosisCathepsin BInflammasomeCaspase 1InflammationAcinar cellChemistryProgrammed cell deathPancreatitisImmunologyBiologyApoptosisMedicineInternal medicineBiochemistryEnzymeInflammasome and immune disordersPancreatitis Pathology and TreatmentStreptococcal Infections and Treatments