SGLT2 inhibitor dapagliflozin alleviates intramyocardial hemorrhage and adverse ventricular remodeling via suppressing hepcidin in myocardial ischemia-reperfusion injury
Rundu Chen, Yingqian Zhang, Haoran Zhang, Hao Zhou, Wei Tong, Yuanbin Wu, Mingrui Ma, Yundai Chen, Yundai Chen
Topics & Concepts
HepcidinMedicineMacrophage polarizationReperfusion injuryDownregulation and upregulationInternal medicineGene knockdownM2 MacrophageMMP9EndocrinologyPharmacologyIschemiaMacrophageInflammationApoptosisChemistryBiochemistryGeneIn vitroDiabetes Treatment and ManagementCaveolin-1 and cellular processesPower Transformer Diagnostics and Insulation