Making a case for using γδ T cells against SARS-CoV-2
Mahboubeh Yazdanifar, Narges Mashkour, Alice Bertaina
Abstract
using existing inexpensive FDA-approved drugs such as bisphosphonate, in order to test its protective immune response to SARS-CoV-2. To support this line of research, we review insights gained from previous coronavirus research, along with recent findings, discussing the potential role of γδ T cells in controlling SARS-CoV-2. We conclude by proposing several strategies to enhance γδ T cell's antiviral function, which may be used in developing therapies for COVID-19.
Topics & Concepts
Immune systemImmunosurveillanceImmunologyCoronavirusT cellMedicineBiologyVirologyCoronavirus disease 2019 (COVID-19)DiseasePathologyInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesImmune Cell Function and Interaction