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Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity

Shuai Jin, Hongyuan Fei, Zixu Zhu, Yingfeng Luo, Jinxing Liu, Shenghan Gao, Feng Zhang, Yu-hang Chen, Yanpeng Wang, Caixia Gao

2020Molecular Cell166 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCas9Cytidine deaminaseComputational biologyGenomegenomic DNACytosineGeneticsCytidineDNAGeneBiochemistryEnzymeCRISPR and Genetic EngineeringPlant Virus Research StudiesChromosomal and Genetic Variations
Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity | Litcius