Consequences of telomere replication failure: the other end-replication problem
Kirsten Ann Brenner, Jayakrishnan Nandakumar
Topics & Concepts
TelomereGenome instabilityDNA replicationTelomeraseBiologyCell biologyControl of chromosome duplicationCarcinogenesisDNA repairGeneticsLicensing factorPre-replication complexEukaryotic DNA replicationDNA damageMitosisDNAGeneTelomeres, Telomerase, and SenescenceDNA Repair MechanismsGenetics, Aging, and Longevity in Model Organisms