PD1 blockade improves survival and CD8+ cytotoxic capacity, without increasing inflammation, during normal microbial experience in old mice
Korbyn J.V. Dahlquist, Matthew A. Huggins, Matthew J. Yousefzadeh, Carolina Soto-Palma, Stephanie H. Cholensky, Mark Pierson, Declan M. Smith, Sara E. Hamilton, Christina D. Camell
Topics & Concepts
Cytotoxic T cellCD8Immune systemInflammationImmunologyT cellEffectorBlockadeReceptorBiologyCancer researchMedicineInternal medicineBiochemistryIn vitroImmune Cell Function and InteractionT-cell and B-cell ImmunologyNeuroinflammation and Neurodegeneration Mechanisms