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COVID-19 symptoms and SARS-CoV-2 infection among people living with HIV in the US: the MACS/WIHS combined cohort study

Gypsyamber DʼSouza, Gayle Springer, Deborah Gustafson, Seble Kassaye, María L. Alcaide, Catalina Ramirez, Anjali Sharma, Frank J. Palella, Phyllis C. Tien, Roger Detels, Mirjam‐Colette Kempf, Cecile D. Lahiri, Charles R. Rinaldo, Audrey L. French, Joseph B. Margolick, Ada A. Adimora

2020HIV Research & Clinical Practice40 citationsDOIOpen Access PDF

Abstract

BACKGROUND: SARS-CoV-2 infection among People Living With HIV (PLWH) is not well-described. OBJECTIVE: To study COVID-19 symptoms and SARS-CoV-2 PCR-based swab testing among participants of the Multicenter AIDS Cohort Study (MACS) and Women's Interagency HIV Study (WIHS). METHODS: A telephone survey was collected April-June 30, 2020. Symptom and testing prevalence were explored. Multivariable logistic regression was used to examine the factors associated with SARS-CoV-2 positivity. RESULTS: = 0.046) and among those living with others versus living alone (aOR = 2.95 95%CI = 1.18-7.40). CONCLUSION: Prevalence and type of COVID-19 symptoms were similar in PLWH and SN. SARS-CoV-2 infection may be elevated among PLWH.

Topics & Concepts

MedicineChillsLogistic regressionmyalgiaCohortInternal medicineHuman immunodeficiency virus (HIV)Cohort studyOddsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Odds ratioCoronavirus disease 2019 (COVID-19)ImmunologyDiseaseInfectious disease (medical specialty)COVID-19 Clinical Research StudiesSARS-CoV-2 detection and testingCOVID-19 Impact on Reproduction