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Identification of novel human USP2 inhibitor and its putative role in treatment of COVID-19 by inhibiting SARS-CoV-2 papain-like (PLpro) protease

Muhammad Usman Mirza, Sarfraz Ahmad, Iskandar Abdullah, Matheus Froeyen

2020Computational Biology and Chemistry41 citationsDOIOpen Access PDF

Topics & Concepts

ProteasesCatalytic triadBiochemistryDocking (animal)ChemistryPapainProteaseBinding siteBiologyEnzymeActive siteMedicineNursingSARS-CoV-2 and COVID-19 ResearchViral Infections and Outbreaks Researchvaccines and immunoinformatics approaches
Identification of novel human USP2 inhibitor and its putative role in treatment of COVID-19 by inhibiting SARS-CoV-2 papain-like (PLpro) protease | Litcius