In silico comparison of spike protein-ACE2 binding affinities across species; significance for the possible origin of the SARS-CoV-2 virus
David A. Winkler, Nikolai Petrovsky, Sakshi Piplani, Puneet Kumar Singh
Abstract
Important: e-prints posted on arXiv are not peer-reviewed by arXiv; they should not be relied upon without context to guide clinical practice or health-related behavior and should not be reported in news media as established information without consulting multiple experts in the field.
Topics & Concepts
AffinitiesContext (archaeology)In silicoSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Computational biology2019-20 coronavirus outbreakBiologyBinding affinitiesEvolutionary biologyVirologyData scienceGeneticsComputer scienceGeneMedicineOutbreakPaleontologyInfectious disease (medical specialty)PathologyReceptorBiochemistryDiseaseSARS-CoV-2 and COVID-19 ResearchBacillus and Francisella bacterial researchViral gastroenteritis research and epidemiology