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Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway

Qingyuan Gao, Meijing Wang, Xiangyi Hou, Meiying Li, Lisha Li

2025Cellular Signalling10 citationsDOI

Topics & Concepts

AdipogenesisRUNX2Mesenchymal stem cellCell biologyCellular differentiationOsteosarcomaOsteoblastChemistryStem cellBiologyIn vitroCancer researchBiochemistryGeneErythrocyte Function and PathophysiologyCellular Mechanics and InteractionsHippo pathway signaling and YAP/TAZ
Substrate stiffness modulates osteogenic and adipogenic differentiation of osteosarcoma through PIEZO1 mediated signaling pathway | Litcius