Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary Aspergillosis
Suresh Ambati, Emma C. Ellis, Tuyetnhu Pham, Zachary Lewis, Xiaorong Lin, Richard B. Meagher
Abstract
Invasive aspergillosis (IA) generally results from a pulmonary infection of immunocompromised patients by the common soil organism and opportunistic pathogen Aspergillus fumigatus . The susceptible population has expanded rapidly due to the increased number of cancer patients with immunocompromising chemotherapy and transplant patients taking immunosuppressants.
Topics & Concepts
Aspergillus fumigatusAntifungalAspergillosisPulmonary aspergillosisOpportunistic pathogenPathogenMedicineFungal pathogenChemotherapyCancerIntensive care medicineImmunologyAspergillusPopulationPathogenic organismMicrobiologyBiologyInternal medicineBacteriaPseudomonas aeruginosaGeneticsEnvironmental healthAntifungal resistance and susceptibilityFungal Infections and StudiesInfectious Diseases and Mycology