Restricting α-synuclein transport into mitochondria by inhibition of α-synuclein–VDAC complexation as a potential therapeutic target for Parkinson’s disease treatment
Megha Rajendran, María Queralt-Martín, Philip A. Gurnev, William M. Rosencrans, Amandine Rovini, Daniel Jacobs, Kaitlin Abrantes, David P. Hoogerheide, Sergey M. Bezrukov, Tatiana K. Rostovtseva
Topics & Concepts
Voltage-dependent anion channelMitochondrionInner mitochondrial membraneCell biologyBiochemistryChemistryMembrane potentialBiophysicsLipid bilayerBiologyMembraneBacterial outer membraneEscherichia coliGeneRNA Interference and Gene DeliveryMitochondrial Function and PathologyEndoplasmic Reticulum Stress and Disease