Rational design, synthesis and biological evaluation of triphenylphosphonium-ginsenoside conjugates as mitochondria-targeting anti-cancer agents
Lu Ma, Xude Wang, Wei Li, Tao Li, Shengnan Xiao, Jincai Lu, Jing Xu, Yuqing Zhao
Topics & Concepts
MitochondrionChemistryCancer cellApoptosisReactive oxygen speciesGinsenosideIn vivoRational designConjugateBiochemistryIn vitroInner mitochondrial membranePharmacologyCancerCancer researchBiologyMedicineGinsengGeneticsMathematical analysisBiotechnologyAlternative medicinePathologyMathematicsGinseng Biological Effects and ApplicationsAutophagy in Disease and TherapyCancer-related molecular mechanisms research