Metformin Use and Vitamin B12 Deficiency in People with Type 2 Diabetes. What Are the Risk Factors? A Mini-systematic Review
Michael Atkinson, Prashamsa Gharti, Thinzar Min
Abstract
In summary, metformin use was associated with lower vitamin B12 concentrations, and higher doses and longer durations of treatment increase the risk of vitamin B12 deficiency. Routine vitamin B12 screening is recommended, prioritizing higher-risk patients. Further research is needed to identify when to initiate monitoring.
Topics & Concepts
MetforminType 2 diabetesVitamin B12MedicineDiabetes mellitusIntensive care medicineInternal medicineEndocrinologyFolate and B Vitamins ResearchDiet and metabolism studiesMetabolism, Diabetes, and Cancer