Litcius/Paper detail

Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities

Jian Song, Shuyu Wang, Xiao Wang, Mei-Qi Jia, Xin-Yi Tian, Xiang-Jing Fu, Cheng‐Yun Jin, Sai‐Yang Zhang

2023Bioorganic Chemistry14 citationsDOI

Topics & Concepts

MAPK/ERK pathwayChemistryKinaseIn vivoPharmacologyCancer cellCancer researchCell growthCancerBiochemistryBiologyGeneticsBiotechnologySynthesis and biological activityMelanoma and MAPK PathwaysCancer Mechanisms and Therapy