Novel organoselenides (NSAIDs-Se derivatives) protect against LPS-induced inflammation in microglia by targeting the NOX2/NLRP3 signaling pathway
Yun-Su Han, Yin Lu, Xin Li, Xiaoqi Niu, Alan K. Chang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli Bi
Topics & Concepts
MicrogliaInflammationNeuroinflammationOxidative stressInflammasomeImmune systemTXNIPChemistryPharmacologySignal transductionCell biologyImmunologyBiologyThioredoxinBiochemistryInflammasome and immune disordersMacrophage Migration Inhibitory FactorNeutrophil, Myeloperoxidase and Oxidative Mechanisms