Structure-based virtual screening of novel USP5 inhibitors targeting the zinc finger ubiquitin-binding domain
Tianhao Wang, Jianbo Tong, Xing Zhang, Zhe Wang, Lei Xu, Peichen Pan, Tingjun Hou
Topics & Concepts
Virtual screeningComputational biologyZinc fingerUbiquitinPlasma protein bindingBiologyChemistryCell biologyBiochemistryDrug discoveryGeneTranscription factorUbiquitin and proteasome pathwaysCancer-related Molecular PathwaysProtein Degradation and Inhibitors