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Cu-Catalyzed decarboxylative annulation of <i>N</i>-substituted glycines with 3-formylchromones: synthesis of functionalized chromeno[2,3-<i>b</i>]pyrrol-4(1<i>H</i>)-ones

Li Chen, Yuan-Da Li, Ying Lv, Zihan Lu, Sheng‐Jiao Yan

2022Chemical Communications20 citationsDOI

Abstract

A novel protocol for the construction of chromeno[2,3 -b ]pyrrol-4(1 H )-ones (CMPOs) 3 from 3-formylchromones, and glycine derivatives via a cascade reaction was developed.

Topics & Concepts

AnnulationChemistryCatalysisTolueneCombinatorial chemistryGlycineDecarboxylationReaction conditionsCascade reactionMedicinal chemistryOrganic chemistryAmino acidBiochemistrySynthesis and Characterization of PyrrolesOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods
Cu-Catalyzed decarboxylative annulation of <i>N</i>-substituted glycines with 3-formylchromones: synthesis of functionalized chromeno[2,3-<i>b</i>]pyrrol-4(1<i>H</i>)-ones | Litcius