In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles
Vladimir V. Botchkarev, Sean C. Harrington, Matteo Stoppato, Alexander Justen, C.D. Kimber, Anjali Kapuria, Keylie M. Gibson, Chi-Shuen Chu, Yuanxin Xu, Kelsey A. Haugh, Ramya Ankala, Nathan H. Kipniss, Andre DeGroot, Emerson Moore, Rowena de Jesus, Funmilola Adewale, Kathy Daniels, Samantha Crocker, Anna Liang, Shannon Joyce, Nicole M. Roberto, Pamela Angel, Derek R. Smith, Athena W. Wong, N. Ortiz de Adler, Valeria Berlfein, Shirisha Amatya, Patricia Cruite, Shariq M. Usmani, Albert Ruzo, Benjamin Ferland, Sundeep Chandra, Edward J. Rebar, Jagesh V. Shah, Kyle Trudeau, Luca Biasco
Topics & Concepts
HaematopoiesisProgenitor cellIn vivoGenome editingBiologyStem cellTransduction (biophysics)Cell biologyIn vitroProgenitorMolecular biologyCell cultureGene deliveryGenetic enhancementVirus-based gene therapy researchCRISPR and Genetic EngineeringPluripotent Stem Cells Research