<i>APOE</i> ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly
Jinping Sun, Zhibao Zhu, Kewei Chen, Dongfeng Wei, Xin Li, Li He, Junying Zhang, Xiaochun Chen, Yaojing Chen, Zhanjun Zhang
Abstract
status with age may be useful in assessing possible mechanisms of disease development in AD.
Topics & Concepts
Apolipoprotein EWhite matterCognitive declineCognitionAllelePsychologyInternal medicineCohortMedicineEffects of sleep deprivation on cognitive performanceGerontologyDiseaseDementiaBiologyNeuroscienceMagnetic resonance imagingGeneticsGeneRadiologyAdvanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments