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Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response

Lee Mulderrig, Juan I. Garaycoechea, Zewen Kelvin Tuong, Christopher L. Millington, Felix A. Dingler, John R. Ferdinand, Liam Gaul, John A. Tadross, Mark J. Arends, Stephen O’Rahilly, Gerry P. Crossan, Menna R. Clatworthy, Ketan J. Patel

2021Nature138 citationsDOIOpen Access PDF

Topics & Concepts

Cockayne syndromeDNA damageEndogenyNeurodegenerationDNA repairBiologyCachexiaCell biologyEndocrinologyInternal medicineNucleotide excision repairMedicineDNAGeneticsDiseaseCancerGDF15 and Related BiomarkersDNA Repair MechanismsRNA modifications and cancer
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response | Litcius