Chloroquine may induce endothelial injury through lysosomal dysfunction and oxidative stress
PauloC. Gregório, Regiane Stafim da Cunha, Gilson Biagini, Bruna Bosquetti, Júlia Budag, Alberto Ortíz, María Dolores Sánchez-Niño, Fellype Carvalho Barreto, Andréa Emília Marques Stinghen
Topics & Concepts
ChloroquineCytotoxicityHydroxychloroquineOxidative stressPharmacologyEndothelial stem cellReactive oxygen speciesEndothelial dysfunctionNitric oxideIn vitroAutophagyEndotheliumChemistryBiologyImmunologyBiochemistryMedicineInternal medicineEndocrinologyApoptosisCoronavirus disease 2019 (COVID-19)DiseaseMalariaInfectious disease (medical specialty)Drug-Induced Ocular ToxicityNeonatal Health and BiochemistryCOVID-19 Clinical Research Studies