Utilization, Yield, and Accuracy of the FilmArray Meningitis/Encephalitis Panel with Diagnostic Stewardship and Testing Algorithm
M. Jana Broadhurst, Shefali Dujari, Indre Budvytiene, Benjamin A. Pinsky, Carl A. Gold, Niaz Banaei
Abstract
The impact of diagnostic stewardship and testing algorithms on the utilization and performance of the FilmArray meningitis/encephalitis (ME) panel has received limited investigation. We performed a retrospective single-center cohort study assessing all individuals with suspected ME between February 2017 and April 2019 for whom the ME panel was ordered. Testing was restricted to patients with cerebrospinal fluid (CSF) pleocytosis. Positive ME panel results were confirmed before reporting through correlation with direct staining (Gram and calcofluor white) and CSF cryptococcal antigen or by repeat ME panel testing.
Topics & Concepts
MedicinePleocytosisMeningitisEncephalitisDiagnostic testRetrospective cohort studyCerebrospinal fluidAlgorithmInternal medicineImmunologyPediatricsComputer scienceVirusBacterial Infections and VaccinesRespiratory viral infections researchPneumonia and Respiratory Infections