Early growth response factor 1 upregulates pro-fibrotic genes through activation of TGF-β1/Smad pathway via transcriptional regulation of PAR1 in high-glucose treated HK-2 cells
P. Xu, Hui Zhan, Rui Zhang, Xiu-jun Xu, Ying Zhang, Le Ying, Jiangang Bi
Topics & Concepts
EGR1SMADDownregulation and upregulationTransforming growth factorCell biologyChemistrySignal transductionThrombinCancer researchMolecular biologyBiologyEndocrinologyInternal medicineGeneMedicinePlateletBiochemistryChronic Kidney Disease and DiabetesBlood Coagulation and Thrombosis MechanismsAcute Kidney Injury Research