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PaRoutes: towards a framework for benchmarking retrosynthesis route predictions

Samuel Genheden, Esben Jannik Bjerrum

2022Digital Discovery53 citationsDOIOpen Access PDF

Abstract

PaRoutes is a framework benchmarking multi-step retrosynthesis methods. It consists of synthetic routes extracted from the patent literature, stock compounds, as well as scripts to compute route quality and route diversity metrics.

Topics & Concepts

BenchmarkingRetrosynthetic analysisComputer scienceScripting languageQuality (philosophy)BusinessProgramming languageOrganic chemistryTotal synthesisChemistryPhilosophyEpistemologyMarketingMachine Learning in Materials ScienceComputational Drug Discovery MethodsProtein Structure and Dynamics
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