Exendin-4 Ameliorates Cardiac Remodeling in Experimentally Induced Myocardial Infarction in Rats by Inhibiting PARP1/NF-κB Axis in A SIRT1-Dependent Mechanism
Refaat A. Eid, Samah Alharbi, Attalla F. El‐kott, Samy M. Eleawa, Mohamed Samir Ahmed Zaki, Fahmy El-Sayed, Muhammad Alaa Eldeen, Hussain Aldera, Abd Al‐Rahman Al‐Shudiefat
Topics & Concepts
Sirtuin 1PARP1Myocardial infarctionCardiac function curveDownregulation and upregulationInflammationVentricular remodelingCardioprotectionInternal medicineEndocrinologyMedicineMessenger RNAApoptosisChemistryNF-κBPharmacologyPoly ADP ribose polymeraseHeart failureEnzymeBiochemistryGenePolymerasePARP inhibition in cancer therapyToxin Mechanisms and ImmunotoxinsIon Channels and Receptors