Exosome-derived miR-372-5p promotes stemness and metastatic ability of CRC cells by inducing macrophage polarization
Xiuru Shi, Ke Wei, Yulun Wu, Lingyu Mao, Wenhao Pei, Haitao Zhu, Yingxiang Shi, Shiwen Zhang, Shuang Tao, Jing Wang, Siyan Pang, Huilan Mao, Wenrui Wang, Qingling Yang, Changjie Chen
Topics & Concepts
MicrovesiclesExosomeMetastasisCancer researchMacrophage polarizationWnt signaling pathwayProtein kinase BTumor microenvironmentmicroRNAPTENChemokineColorectal cancerCateninBiologyPI3K/AKT/mTOR pathwayMedicineMacrophageCancerImmunologySignal transductionCell biologyInflammationInternal medicineIn vitroTumor cellsGeneBiochemistryExtracellular vesicles in diseaseMicroRNA in disease regulationCircular RNAs in diseases