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Necroptosis blockade prevents lung injury in severe influenza

Avishekh Gautam, David F. Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Lee-Ann Van de Velde, Jessica A Gaevert, Victoria Meliopoulos, Bikash Thapa, Diego A. Rodríguez, Kathy Q. Cai, Chaoran Yin, Daniel Schnepf, Julius Beer, Carly DeAntoneo, Riley Williams, Maria Shubina, Brandi Livingston, Dingqiang Zhang, Mark Andrake, Seungheon Lee, Raghavender Boda, Anantha Lakshmi Duddupudi, Jeremy Chase Crawford, Peter Vogel, Christian Loc’h, Martin Schwemmle, Lawrence C. Fritz, Stacey Schultz‐Cherry, Douglas R. Green, Gregory D. Cuny, Paul G. Thomas, Alexei Degterev, Siddharth Balachandran

2024Nature111 citationsDOIOpen Access PDF

Topics & Concepts

NecroptosisARDSInflammationMedicineBlockadeInfluenza A virusLungImmunologyImmune systemDiffuse alveolar damageVirusBiologyReceptorProgrammed cell deathAcute respiratory distressApoptosisInternal medicineBiochemistryCell death mechanisms and regulationinterferon and immune responsesViral Infections and Outbreaks Research
Necroptosis blockade prevents lung injury in severe influenza | Litcius