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Development, Optimization, and in vitro Evaluation of Silybin-loaded PLGA Nanoparticles and Decoration with 5TR1 Aptamer for Targeted Delivery to Colorectal Cancer Cells

Seyyed Mobin Rahimnia, Majid Saeedi, Jafar Âkbari, Katayoun Morteza‐Semnani, Akbar Hedayatizadeh‐Omran, Rezvan Yazdian‐Robati

2024AAPS PharmSciTech20 citationsDOI

Topics & Concepts

PLGACytotoxicityZeta potentialDispersityDrug deliveryChemistryNanoparticleCancer cellIn vitroMTT assayDifferential scanning calorimetryBiophysicsNuclear chemistryNanotechnologyMaterials scienceCancerOrganic chemistryBiochemistryMedicineBiologyPhysicsInternal medicineThermodynamicsSilymarin and Mushroom PoisoningSynthesis and bioactivity of alkaloidsDrug Solubulity and Delivery Systems
Development, Optimization, and in vitro Evaluation of Silybin-loaded PLGA Nanoparticles and Decoration with 5TR1 Aptamer for Targeted Delivery to Colorectal Cancer Cells | Litcius