D–π–A azine based AIEgen with solvent dependent response towards a nerve agent
Munusamy Sathiyaraj, Viruthachalam Thiagarajan
Abstract
the formation of a new intramolecular charge transfer state in pure tetrahydrofuran (THF). In the aggregated state, DPBN shows blue shifted emission with fluorescence enhancement in THF-water mixture by protonation at the amine nitrogen centre. Thus, DPBN can be used as a diagnostic measure to selectively detect nerve agents like DCP. This study also paves the way for further development of molecular probes for nerve agents that would represent immense implications in various fields of chemistry and biology.
Topics & Concepts
AzineSolventChemistryNerve agentCombinatorial chemistryNuclear chemistryOrganic chemistryEnzymeAcetylcholinesteraseLuminescence and Fluorescent MaterialsMolecular Sensors and Ion DetectionSynthesis and Characterization of Heterocyclic Compounds