Prognostic significance of survival-associated alternative splicing events in gastric cancer
Shichao Zhang, Zuquan Hu, Yingwu Lan, Jinhua Long, Yun Wang, Xiaowen Chen, Xiaofeng Xu, Zhu Zeng, Yan Ouyang
Abstract
as hub splicing factors, and the focal adhesion signaling pathway was most significantly correlated with survival-associated alternative splicing events. The results of this study may establish a foundation for further research investigating the underlying mechanism of alternative splicing events in the progression of gastric cancer.
Topics & Concepts
Alternative splicingCancerMedicineInternal medicineOncologyBioinformaticsBiologyGeneticsGeneMessenger RNARNA Research and SplicingRNA modifications and cancerRNA and protein synthesis mechanisms