SS-31 inhibits mtDNA–cGAS–STING signaling to improve POCD by activating mitophagy in aged mice
Yelong Ji, Yuanyuan Ma, Yimei Ma, Ying Wang, Xining Zhao, Danfeng Jin, Xu Li, Shengjin Ge
Topics & Concepts
MitophagyNeuroprotectionNeuroinflammationPharmacologyAgonistMedicineGene knockdownChemistryCell biologyInflammationImmunologyBiologyInternal medicineApoptosisAutophagyBiochemistryReceptorinterferon and immune responsesNeuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders