ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
Cheng Wang, Mingzi Zhang, Gustavo Garcia, Erpo Tian, Qi Cui, Xianwei Chen, Guihua Sun, Jinhui Wang, Vaithilingaraja Arumugaswami, Yanhong Shi
Topics & Concepts
BiologyAstrocyteInduced pluripotent stem cellCoronavirus disease 2019 (COVID-19)OrganoidSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Apolipoprotein EHuman Induced Pluripotent Stem CellsNeuronVirology2019-20 coronavirus outbreakDiseaseNeuroscienceImmunologyCell biologyPathologyInfectious disease (medical specialty)GeneGeneticsCentral nervous systemMedicineOutbreakEmbryonic stem cellLong-Term Effects of COVID-19SARS-CoV-2 and COVID-19 ResearchNeuroinflammation and Neurodegeneration Mechanisms