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Long-term Positivity to SARS-CoV-2: A Clinical Case of COVID-19 with Persistent Evidence of Infection

Damiano D’Ardes, Andrea Boccatonda, Ilaria Rossi, Michela Pontolillo, Giulio Cocco, Cosima Schiavone, Francesca Santilli, Maria Teresa Guagnano, Marco Bucci, Francesco Cipollone

2020European Journal of Case Reports in Internal Medicine16 citationsDOIOpen Access PDF

Abstract

In December 2019, an outbreak of a new coronavirus (SARS-CoV-2) was reported in Hubei province in China. The disease has since spread worldwide and the World Health Organization declared it a pandemic on 11 March 2020. We describe the case of a 65-year-old woman who clinically recovered from COVID-19 but showed persistent infection with SARS-CoV-2 for 51 days. LEARNING POINTS: A case of persistent infection with SARS-CoV-2 is described.Some tests may pick up viral RNA fragments, giving a false positive result.The quarantining of infected patients to limit possible SARS-CoV-2 spread is important.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)MedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicOutbreak2019-20 coronavirus outbreakBetacoronavirusCoronavirusPediatricsVirologyDiseaseInfectious disease (medical specialty)Internal medicineCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19