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ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut

Mengze Lyu, Hiroaki Suzuki, Lan Kang, Fabrina Gaspal, Wenqing Zhou, Jérémy Goc, Lei Zhou, Jordan Zhou, Wen Zhang, JRI Live Cell Bank, David Artis, Randy Longman, Gregory F. Sonnenberg, Ellen Scherl, Robbyn Sockolow, Dana J. Lukin, Robert Battat, Thomas Ciecierega, Aliza Solomon, Elaine Barfield, Kimberley Chien, Johanna Ferriera, Jasmin Williams, Shaira Khan, Peik Sean Chong, Samah Mozumder, Lance Chou, Wenqing Zhou, Anees Ahmed, Connie Zhong, Ann Mary Joseph, Sanchita Kashyap, Joseph Gladstone, Samantha N. Jensen, Zeli Shen, James G. Fox, Robbyn Sockolow, Terri M. Laufer, Yong Fan, Gérard Eberl, David R. Withers, Gregory F. Sonnenberg

2022Nature278 citationsDOIOpen Access PDF

Topics & Concepts

Innate lymphoid cellRAR-related orphan receptor gammaBiologyImmunologyImmune systemMajor histocompatibility complexRegulatory T cellMucosal immunologyAntigen-presenting cellAntigen presentationFOXP3T cellCell biologyImmunityIL-2 receptorIL-33, ST2, and ILC PathwaysImmune Cell Function and InteractionEosinophilic Esophagitis
ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut | Litcius