Discovery of facile amides-functionalized rhodanine-3-acetic acid derivatives as potential anticancer agents by disrupting microtubule dynamics
Xiang Zhou, Jiamin Liu, Jiao Meng, Yihong Fu, WU Zhi-bin, Guiping Ouyang, Zhenchao Wang
Abstract
-phenylacetamide derivatives could have utility for the development of microtubule-stabilising therapeutic agents.
Topics & Concepts
RhodanineChemistryAcetic acidCombinatorial chemistryMicrotubuleOrganic chemistryBiologyCell biologyCancer therapeutics and mechanismsChemical Synthesis and AnalysisChemical Reaction Mechanisms