Potential compounds from several Indonesian plants to prevent SARS-CoV-2 infection: A mini-review of SARS-CoV-2 therapeutic targets
Didi Nurhadi Illian, Etti Sartina Siregar, Sumaiyah Sumaiyah, Ahmad Rusdan Handoyo Utomo, Arif Nuryawan, Mohammad Basyuni
Abstract
), RNA-dependent RNA polymerase (RdRp), helicase, and serine protease. Indonesia is rich in medicinal plants (herbal); it also has a long history of using plants to treat various hereditary diseases. However, since SARS-CoV-2 is a new disease, it has no history of plant-based treatment anywhere in the world. This mini-review describes natural products from several Indonesian plants that contain compounds that could potentially prevent or reduce SARS-CoV-2 infection, act as potential targeted therapy, and provide new therapeutic strategies to develop SARS-CoV-2 countermeasures.
Topics & Concepts
VirologyProteaseBiologyCoronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ProteasesIndonesianOutbreakCoronavirus disease 2019 (COVID-19)DiseaseMedicineEnzymeInfectious disease (medical specialty)BiochemistryPathologyPhilosophyLinguisticsMedicinal Plant ResearchTransgenic Plants and ApplicationsSARS-CoV-2 and COVID-19 Research