Visible light metallaphotoredox catalysis in the late-stage functionalization of pharmaceutically potent compounds
Praveen P. Singh, Pravin K. Singh, Vishal Srivastava
Abstract
The late stage functionalization (LSF) is a distinctive approach for accelerating the discovery of structure–activity relationships (SARs) and optimising ADME (absorption, distribution, metabolism, and excretion) profiles.
Topics & Concepts
ChemistrySurface modificationCatalysisCombinatorial chemistryStage (stratigraphy)Organic chemistryPhysical chemistryBiologyPaleontologyRadical Photochemical ReactionsSynthesis and Catalytic ReactionsSulfur-Based Synthesis Techniques